← Influencer libraryEdition 2026-10-10, preview.
THE LIBRARY

Sarah Guo

885 items collected

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“you can’t do critical research without the compute scale of the top frontier labs” Nick: hold my beer

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OpenAI took 25% of its production engineers off every project and told them: you are just securing now. Their top model hunted in their infrastructure until it saturated (stopped finding new issues). Will everyone else follow? New physics of cybersecurity @gdb / @NoPriorsPod https://t.co/keFxPHcXsT

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What are the Post-AGI Rules of the Game in Cyber and Science? New @NoPriorsPod with @gdb Co-founder/President of @OpenAI 01:11 – AI and Advancements in Mathematics 05:55 – AI Communication and Oversight 07:45 – AI for Overcoming Biology Data Bottlenecks 11:28 – Revolutionizing Drug Discovery 14:18 – Changing Regulations to Accelerate Progress 16:51 – Dots the Proactive Agent 19:19 – Unifying Work and Consumer Agents 22:02 – How UI Will Evolve 26:08 – Cybersecurity in the AI Age 32:55 – The Change in the Physics of Cybersecurity 35:49 – OpenAI’s Human-Centric Ethos not covered: his signature full interview on YT or anywhere you get your pod…

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Why join Ithaca: @GuptaRK22 & @johnwhegeman are taking Bumble private, and we led the round behind it. It’s our largest single round investment by a lot. John is the only CRO of a company with $200B in annual revenue I've met who is an engineer's engineer. He ran engineering across News Feed and Monetization before becoming Meta's CRO. I tried to recruit Ravi years ago and he had the best references I've ever gotten on a leader. My partner @mvernal introduced them to each other. He'd worked with both. We are full conviction in these people, to the point where we rethought our own business model in order to be able to back them, and it wasn’…

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Congratulations to MSFT! A rich ecosystem of silicon innovation is critical to broad benefit from intelligence

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personal agents, the end of friction, economic consequences of finally getting around to it https://t.co/jEOtEaFvbx Personal Agent Protocol Interview by @noahrshinn instinct founder @noahrshinn .@jgebbia and NDS launch of https://t.co/6bM9MYYZf0

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How much time we now spend peering into a machine’s thought process "It is impossible to say just what I mean! / But as if a magic lantern threw the nerves in patterns on a screen"

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@JayaGup10 Of course if the next company wants to sell $20M of inference at negative gross margin, with no path to scale supply, be my guest. 🙇‍♀️

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lots of discussion of capital gathering and allocation in the ai era but capital allocation was always one of the most important executive skills, the stakes have just scaled up. it’s that and hiring talented drivers, building cultures that can execute

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the simplest fucking thing in the world is to act fairly rather than take advantage of the people who aren’t a pain in your ass, and are unequivocally on your side

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ICYMI, new @NoPriorsPod with @reflection_ai cofounder @MishaLaskin on China, safety, market structure of ai, the business model of open models, reasoning efficiency, distillation, and what it takes to ship massive frontier AI “Competitive tension is just good.” https://t.co/K6w56NW6OT wherever you get your pods, or YouTube https://t.co/rW3dH7WxyK

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the next set of startups that will grow rapidly, with margin despite not being “tech companies” are cyber incident response companies

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a full day of researchers arguing about inference and the future is my idea of a good time All-Gather, Nov 18 in SF!

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flashscaling = decade of growth in a year there is a small handful of companies (including the labs) scaling like no company ever before, and 1) the GTM folks and 2) finance/compute folks at those companies will have uniquely in-demand experience in the next era there’s obviously never been a more interesting time to build product… but there has also never been a more interesting time to lead sales or finance! what sales hiring, training, comp cycles are compressible? what business models align with customers? how to preserve margin/manage supply risk? if intelligence makes products ~universally better, how much can we spend on compute? wh…

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how will businesses talk to their customer’s personal agents? relentless innovation from team @SierraPlatform: the Personal Agent Protocol

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Finally, le chonk! 🐱 Counting this team out was a mistake - let the open model teams cook

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no, actually you can treat seed investments you lead as full bets, and work on them with committed belief for years founders do that, every time structure determines strategy

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congratulations team @reflection_ai ☀️ future is bright with western open frontier models ☀️

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the choice of whether to resist the future or rapidly adapt. some strategic wisdom from our partner @mvernal

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Really fun @NoPriorsPod with @goodwin_ml founder of @fractile_ai topics: - how to win the ai chip market, structurally - ai for chip design, what’s compressible - the need to be a frontier lab to serve frontier labs - solving memory bandwidth - new hardware scaling laws https://t.co/LcZGB33XPm full interview on YouTube or anywhere you get your podcasts https://t.co/mwJ1ZQenf1

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Edition 2026-10-10, preview.